The Museo Alejandro de Humboldt (Alejandro de Humboldt Museum) is located in a Colonial house in Plaza de San Francisco de Asís Square, in Old Havana, Cuba. Its name comes from the German scientist Alejandro von Humboldt, who is seen as the second person to discover Cuba. This is a scientific museum dedicated to biology and its main objective is to preserve research and promote the historical Humboldt’s legacy. This institution enhances the labor of Cuban and international personalities whose contributions are considered relevant for the development of culture in general terms. It exhibits the historical trajectory of the scientific and botanic data he compiled throughout the island at the beginning of the 19th century, as well as a botanic exhibition which is fundamentally made up of ferns. In this museum there is a perfect copy of a Kritosaurus skeleton found in the desert and donated by the Mexican government, as well as an enormous Pterosaur skeleton, which is around 10 meters length. The House also has a conference room with capacity for 100 persons and a specialized library on German literature.

The Museo de Arte Colonial (Colonial Art Museum) is housed within the oldest construction in Old Havana, the Condes de Casa Bayona Palace, a mansion rebuilt in 1720 by Cuban Governor, Don Luis Chachón. The palace’s Classical patio and coffered ceiling made intricately of wood stand out within this construction. The palace boasts a wonderful location, right in front of the San Cristóbal de La Habana Cathedral. This small museum has a Colonial furniture and decorative art exhibition, amongst which will stand out some pottery with Colonial Cuba motifs, as well as several scenes of Colonial dining rooms and a fantastic collection of ornamental flowers.

Situated in the former Presidential Palace (1920-1960), the Museum of the Revolution is a colorful building of a large dome and a mixture of styles. A detailed panorama of the struggle undertaken by the Cuban people in order to obtain its freedom is available in its 38 rooms. Its outdoor areas feature the Granma Memorial, where visitors can see, protected by an enormous glass case, the boat on which Fidel Castro and more than eighty combatants returned to Cuba from exile in Mexico to recommence the fight for the country's independence.

Plaza de Armas surrounds a statue of the patriot Céspedes and is ringed by shaded marble benches and second-hand bookstalls. This square, founding in 1519, was the city's first open space, around which the most important political, military, religious and civil institutions were located. The palaces that surrounded it during the 18th century are worthy exponents of Cuban Baroque architecture. On the square’s eastern side a small neoclassical temple, El Templete, marks the spot where the first Catholic mass was celebrated in 1519. Next door is one of the city’s most luxurious hotels, Hotel Santa Isabel. To the north, the squat but angular and moated Castillo de la Real Fuerza (Fort of the Royal Forces) is one of the oldest forts in the Americas.