The Cathedral of Havana is an iconic work of what is known as Cuban Baroque and the most remarkable of our colonial churches. The glorious baroque facade and asymmetrical bell-towers of the late 18th-century cathedral are the square’s top attraction. Its interior is surprisingly plain, but it once held the remains­ of Christopher Columbus. Religious services are held here. It has been declared a National Monument.

The Museo Alejandro de Humboldt (Alejandro de Humboldt Museum) is located in a Colonial house in Plaza de San Francisco de Asís Square, in Old Havana, Cuba. Its name comes from the German scientist Alejandro von Humboldt, who is seen as the second person to discover Cuba. This is a scientific museum dedicated to biology and its main objective is to preserve research and promote the historical Humboldt’s legacy. This institution enhances the labor of Cuban and international personalities whose contributions are considered relevant for the development of culture in general terms. It exhibits the historical trajectory of the scientific and botanic data he compiled throughout the island at the beginning of the 19th century, as well as a botanic exhibition which is fundamentally made up of ferns. In this museum there is a perfect copy of a Kritosaurus skeleton found in the desert and donated by the Mexican government, as well as an enormous Pterosaur skeleton, which is around 10 meters length. The House also has a conference room with capacity for 100 persons and a specialized library on German literature.

The Simón Bolívar Museum is situated within an old Neoclassical palace dating back to between 1806 and 1817., right in front of the bronze statue of Latin America’s liberator, in Old Havana. This museum in honor of Simón Bolívar was opened July 24th 1993, coinciding with the anniversary of his birth. It has permanent exhibitions dealing with the history of the Bolivarian nation and its main figures of independence. The museum also houses a great library with important book collections and Latin-American documents.

A few steps towards Calle Brasil from Plaza del Cristo Square is where the 1886 Museo de la Farmacia Habanera is located. Founded by the Catalonian José Sarrá, it is a shop-museum and nowadays still functions as a pharmacy. The museum displays the history of pharmacies in Havana and their evolution in Cuba. This Pharmacy preserves its original Neo-gothic furniture with Moorish influences, and host a large collection of medicine bottles and medical tools, extracted from archeological excavations in the old city, as well as a book collection with valuable prescriptions for the study of Cuban pharmacopoeia. The museum also exhibits an elegant scale model of an old pharmacy with captivating historical explanations.