A few steps towards Calle Brasil from Plaza del Cristo Square is where the 1886 Museo de la Farmacia Habanera is located. Founded by the Catalonian José Sarrá, it is a shop-museum and nowadays still functions as a pharmacy. The museum displays the history of pharmacies in Havana and their evolution in Cuba. This Pharmacy preserves its original Neo-gothic furniture with Moorish influences, and host a large collection of medicine bottles and medical tools, extracted from archeological excavations in the old city, as well as a book collection with valuable prescriptions for the study of Cuban pharmacopoeia. The museum also exhibits an elegant scale model of an old pharmacy with captivating historical explanations.

The Catedral Ortodoxa de Nuestra Señora de Kazán (Nuestra Señora de Kazán Orthodox Cathedral), declared World Heritage Site by UNESCO, is one of the newest constructions in Havana, being built in 2000. This Russian Orthodox church is Byzantine in style. It has six beautiful domes, two of which (the biggest and smallest) are gold-sheeted, and the rest are made of bronze. Its staircase entrance calls our attention and is considered the second largest staircase of all outside Russia. From the interior, its golden altar stands out, built in Trinidad and the San Sergio Monastery, Russia; and the murals adorning its walls.

The Convento de Santa Clara (Santa Clara Convent) is located at the south of Plaza Vieja Square of Havana. This is the biggest and oldest convent in all of Cuba, built between 1638 and 1643, and it is a good example of early Spanish influenced architecture. It was actually the first female convent in the city. The temple stopped serving for religious purposes in 1920, housing for some time the Ministry of Public Works. It is currently part of the restoration team of Old Havana. It being recommended to visit the Colonial-style interior patio, where the first public fountain of the city was found; the cloister, the cells of the nuns and the small cemetery.

Plaza de Armas surrounds a statue of the patriot Céspedes and is ringed by shaded marble benches and second-hand bookstalls. This square, founding in 1519, was the city's first open space, around which the most important political, military, religious and civil institutions were located. The palaces that surrounded it during the 18th century are worthy exponents of Cuban Baroque architecture. On the square’s eastern side a small neoclassical temple, El Templete, marks the spot where the first Catholic mass was celebrated in 1519. Next door is one of the city’s most luxurious hotels, Hotel Santa Isabel. To the north, the squat but angular and moated Castillo de la Real Fuerza (Fort of the Royal Forces) is one of the oldest forts in the Americas.