A few steps towards Calle Brasil from Plaza del Cristo Square is where the 1886 Museo de la Farmacia Habanera is located. Founded by the Catalonian José Sarrá, it is a shop-museum and nowadays still functions as a pharmacy. The museum displays the history of pharmacies in Havana and their evolution in Cuba. This Pharmacy preserves its original Neo-gothic furniture with Moorish influences, and host a large collection of medicine bottles and medical tools, extracted from archeological excavations in the old city, as well as a book collection with valuable prescriptions for the study of Cuban pharmacopoeia. The museum also exhibits an elegant scale model of an old pharmacy with captivating historical explanations.

Plaza de Armas surrounds a statue of the patriot Céspedes and is ringed by shaded marble benches and second-hand bookstalls. This square, founding in 1519, was the city's first open space, around which the most important political, military, religious and civil institutions were located. The palaces that surrounded it during the 18th century are worthy exponents of Cuban Baroque architecture. On the square’s eastern side a small neoclassical temple, El Templete, marks the spot where the first Catholic mass was celebrated in 1519. Next door is one of the city’s most luxurious hotels, Hotel Santa Isabel. To the north, the squat but angular and moated Castillo de la Real Fuerza (Fort of the Royal Forces) is one of the oldest forts in the Americas.  

The Real Force Castle is located in Old Havana, in an attractive area of important architectural, urban, cultural and social values. This is the oldest fortress of the former fortification system of Havana and the Americas, which construction dates back to 1577. It was declared a World Heritage Site by UNESCO. A replica of the La Giraldilla, the symbol of the city, can be seen on the highest tower of the castle (the original is in the Museum of the City). Since 2008, the Museo de Navegación (Maritime Museum) is located in the former moat of the Real Force Castle. This museum houses interesting exhibits detailing the history of the fortress and Old Havana, as well as its connections with the former Spanish Empire. It’s worth mentioning that huge scale model of the Santísima Trinidad galleon can be found here.

This square dates back to the first half of the 17th century. Its location, just a few metres from the bay, led to it becoming an important trading square over the years. It is said that around the year 1600 the first fountain of the city could be seen at this square. In 1836 it was replaced by a beautiful fountain made of white Carrara marble by Giuseppe Gaggini, under the good auspices of the Villanueva Count. This fountain is called Fuente de los Leones (Lions Fountain). On its paved area stand two noteworthy buildings: the Monastery and Basilica of San Francisco de Asís, which today houses the Museum of Religious Art and a concert hall. It is also where the Lonja del Comercio (Chamber of Commerce) is located, inspired by Spanish Renaissance architecture and topped by a dome on which a sculpture of the god Mercury stands. Among the houses built around the plaza, the house of the Arostegui family, residence of the Captain Generals until the completion of the City Hall at the end of the 18th century, was erected.