This museum is located in the former Moncada Barracks, a military fortification which came under attack on 26 July 1953 by a group of young revolutionaries led by Fidel Castro Ruz. Moncada was the second military fort of the country, occupied by about a thousand men under the command of Fulgencio Batista. Unfortunately, the rebels were either killed or captured. Although unsuccessful, the attack ignited the sparks of Cuban Revolution. Fidel wrote his famous speech "La historia me absolverá" ("History will absolve me"), which was smuggled out of prison, printed, and distributed throughout the island. This event launched the final stage of the struggle for the country's freedom. After the victory of the revolution Moncada Barrack was transformed into a school, and a space was devoted to Museum. The museum exhibits some of the revolutionaries' personal belongings, some of the weaponry used and photographs of the historical event, as well as a valuable coin collection.

Cuba's oldest museum was founded in 1899 by Emilio Bacardí Moreau, the former Santiago mayor whose rum-making family fled to Puerto Rico after the Revolution. It is just a few metres from the Parque Céspedes, in the heart of the city. The museum has an excellent collection of Cuban art, as well as some European works, some items from the wars of independence and an archaeological hall that features a 3,000-year-old Egyptian mummy, two Peruvian skeletons and a shrunken head. It houses the most important painting gallery in Cuba, displaying an enviable collection of colonial painting dating back two centuries.

The Spanish fortress known as El Morro, south of Santiago, was constructed between 1638 and 1700 and was designed by Giovanni Antonelli, the Italian architect and engineer responsible for fortresses bearing the same name in both Havana and San Juan, Puerto Rico. El Morro was built to ward off pirates (and rebuilt after a 1662 attack by the English pirate Henry Morgan). Today, its solid walls house the Museum of Piracy, its rooms also reflects the main events connected with the naval battle of Santiago de Cuba, episode of the Spanish-Cuban-American in 1898 and photographs related to the events of Maine , the Spanish and U.S. military leaders, Admiral Pascual Cervera and Vice Admiral Sampson and planes and coastal defenses and batteries of El Morro. There are wonderful views from interior rooms, which have wooden floors and stone walls, as well as from various terraces.

The Granjita Siboney Museum is located in the road to Playa Siboney Beach, in the province of Santiago de Cuba. It is the former encampment from where the youngsters that took the Moncada Headquarters, the second military fortress in the city of Santiago de Cuba, on July 26th 1953 left. In the 7 exhibition rooms of this museum you’ll also discover the historic house, the previous preparations to the famous assault, the development and the consequences it had for Cuba. It exhibits valuable documents and personal objects of some of the intrepid young rebels. Among its most valued objects are the semiautomatic M-1 with folded butt used by the revolutionaries during the assault, sports rifle, uniforms, documents, photographs.